Author

Xin-Yu Yang

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Open access Sep 2026

Inflammation, coagulation, and nutritional reserves refine 90-day prognostic stratification after ruptured intracranial aneurysm repair

Background Ruptured intracranial aneurysm is a major cause of neurological disability. Existing prognostic models primarily rely on neurological and radiological severity and may overlook systemic biological alterations. Objective To evaluate whether integrating systemic immune-inflammation index (SII), D-dimer, and pr...

Jian Li, Zhen Wang, Hong-Wen Li et al. · Frontiers in Nutrition · 0 citations

Open access Oct 2026

Ferroptosis-associated candidate genes in aneurysmal subarachnoid hemorrhage: evidence from human peripheral blood and mouse brain

Aneurysmal subarachnoid hemorrhage (aSAH) has high morbidity and mortality. Ferroptosis may contribute to aSAH-related brain injury, but its peripheral and brain-associated signatures remain unclear. Human peripheral-blood dataset GSE36791 (43 aSAH, 18 controls) was analyzed using limma, FerrDb intersection,...

Jia Li, Cong Wang, Hong-Wen Li et al. · Frontiers in Neurology · 0 citations

Open access Sep 2026

Explainable machine learning for 2-year functional outcomes in older adults with aneurysmal subarachnoid hemorrhage in North China: external validation and health-system context

Background Older adults with aneurysmal subarachnoid hemorrhage (aSAH) have heterogeneous long-term outcomes, and differences in treatment pathways and hospital capacity may complicate early risk stratification. Methods This multicenter cohort study included adults aged ≥60 years with aSAH in North China. Of 1,132 admi...

Wen-Gao Zhang, Gang Li, Xi-Rui Wang et al. · Frontiers in Neurology · 0 citations