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Open access Sep 2026

Beauvericin exhibits antitumor activity in pancreatic cancer cells: Integrative analysis suggests potential modulation of the KEAP1-NRF2-HMOX1 axis and survival signaling pathways

To investigate the anticancer effects of Beauvericin (BEA) and elucidate its potential mechanisms in pancreatic cancer cells, a malignancy characterized by marked heterogeneity and frequent chemoresistance. The effects of BEA on the proliferation, migration and apoptosis of Mia PaCa-2 cells were evaluated via CCK-8,...

Xin-Yi Yu, Xiao-Dan Liu, Jie Ouyang et al. · 0 citations
Open access Aug 2026

Improving the preoperative diagnosis of invasive lung adenocarcinoma by combining multiplanar volume rendering (MPVR)-based solid component measurement with pathological analysis

Background The early diagnosis of lung adenocarcinoma (LUAD) remains challenging. Multiplanar volume rendering (MPVR) has demonstrated good diagnostic performance; however, misclassification can still occur. This study investigated the pathological basis of MPVR misclassification and developed a model to improve the pr...

Min Zhao, Zhi-Yu Zhang, Xin-Yi Yu et al. · 0 citations

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