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Sep 2026

Quercetin protects against murine cytomegalovirus-induced pneumonia via suppression of viral replication and NLRP3 inflammasome activation.

Cytomegalovirus (CMV)-induced pneumonia is associated with excessive pulmonary inflammation and severe lung injury, particularly in immunocompromised individuals. Effective therapeutic strategies targeting both viral replication and inflammation-driven lung damage remain limited. Quercetin, a naturally occurring flavon...

Ping Sun, Xin-Xiang Chen, Xiao-Juan Wang et al. · 0 citations
Aug 2026

Vilazodone inhibits NLRP3 inflammasome assembly by targeting the NACHT domain and alleviates inflammatory disease.

Vilazodone exerted anti-inflammatory effects in vivo, reducing cytokine production in mouse models of MSU-induced peritonitis and LPS-induced systemic inflammation and highlight its potential for repurposing in inflammasome-driven diseases.

Xiang-Yu Yang, Gui-Fang Xiong, Jie Yang et al. · 0 citations

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