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Xin-Yi Liu

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Open access Sep 2025

Profiling of terminating ribosomes reveals translational control at stop codons

A profiling strategy to capture terminating ribosomes in mammalian cells is established and a substantial heterogeneity in ribosome pausing at individual stop codons is revealed, established as a distinct translational signature shaped by mRNA sequence contexts, ribosome heterogeneity, and cell type-specific translational control.

Longfei Jia, Yuanhui Mao, Saori Uematsu et al. · 4 citations
Open access Jul 2026

Profiling of terminating ribosomes reveals translational control at stop codons

A profiling strategy to capture terminating ribosomes in mammalian cells is established and a substantial heterogeneity in ribosome pausing at individual stop codons is revealed, suggesting termination pausing as a distinct translational signature shaped by mRNA sequence contexts, ribosome heterogeneity, and cell type-specific translational control.

Longfei Jia, Yuanhui Mao, Saori Uematsu et al. · 1 citation

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