Author

Xin-Yan Qu

3 papers indexed here

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Open access Oct 2026

Aqueous Extract of Lonicerae japonicae Flos Attenuates Alcohol-Associated Liver Disease by Suppressing Oxidative Stress and Inflammation in Mice

Objectives: This study employed an integrative strategy combining UPLC-MS-based phytochemical profiling, network pharmacology, and transcriptomics to systematically investigate the protective effects and potential mechanisms of LJF against ALD. Methods: An ALD model was established via chronic ethanol liquid diet feedi...

Lin Chen, Meng-Jie Zhang, Dong-Sheng Zhao et al. · Pharmaceuticals · 0 citations

Aug 2026

Hydroxyethyl starch serves as a superior vehicle for colon-targeted delivery of indole-3-acetic acid to enhance therapeutic efficacy against colitis.

Indole-3-acetic acid (IAA), a crucial tryptophan-derived metabolite, exerts anti-inflammatory and immunomodulatory effects primarily through activation of aryl hydrocarbon receptor (AhR) and modulation of gut immune homeostasis, providing a mechanistic rationale for its use in colitis. Colon-targeted delivery of IAA to...

Lin Tian, Qian Gong, Wen-Shan Yang et al. · International Journal of Bio... · 1 citation

Open access Sep 2026

HAMSIAA protects cyclophosphamide induced immunosuppression by modulating gut homeostasis and purine metabolism

Introduction Dietary supplementation with functional starches serves as a promising intervention strategy for immune regulation, yet the immunomodulatory efficacy and underlying mechanisms of newly developed modified starch derivatives remain to be further explored. In this study, a cyclophosphamide (CTX) induced secon...

Di Zhang, Ying-Ying Song, Shi-Hao Guo et al. · Frontiers in Immunology · 0 citations