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Open access Sep 2026

Symptom clusters and quality of life among patients with thyroid cancer during early survivorship: a national multicenter cross-sectional study

Symptom clusters are prevalent among patients with thyroid cancer during early survivorship and are significantly associated with poorer quality of life, while female patients and those undergoing total thyroidectomy may be at increased risk for poorer quality of life.

Jie Gao, Xin Wang, Jia-Yan Cao et al. · 0 citations
Open access Aug 2026

Engineered Red Blood Cell-Derived Nanovesicles Functionalized with cRGD Peptide and Loaded with Acevaltrate for Targeted Ferroptosis Therapy of Triple-Negative Breast Cancer

Triple-negative breast cancer (TNBC) remains a highly aggressive breast cancer subtype with limited molecularly targeted treatment options, while acevaltrate (ACE), a natural dual-target ferroptosis inducer, is constrained by poor aqueous solubility and insufficient tumor accumulation. Here, we engineered cyclic Arg-...

Fu-Lan Yang, Xun Xi, Yue Yu et al. · 0 citations
Open access Aug 2026

Trastuzumab-TKI combination in HER2-Positive tumors: a FAERS-Based safety profile and multimodal analysis of Tanespimycin’s role in enhancing targeting of the HSP90AA1-PI3K-Akt-mTOR axis

Background This study addresses the safety profiles and molecular mechanisms of trastuzumab monotherapy and its combination with lapatinib, neratinib, and tucatinib for treating HER2-positive tumors. Methods The research integrates a multi-platform approach, including data from the US Food and Drug Administration Adver...

Xiao Chen, Xiao Han, Yuan-Yuan Zhang et al. · 0 citations

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