Integrative Single‐Cell Transcriptomics, Multi‐Omics Analyses, and Computational Pharmacology Reveal Macrophage Heterogeneity and the Putative THBS1‐CD36 Axis in Coronary Atherosclerosis
ABSTRACT Coronary atherosclerosis (CA) is characterized by profound macrophage heterogeneity that drives plaque progression and vulnerability, yet the precise subpopulations and their niche‐specific functions remain incompletely defined. Here, we constructed a single‐cell transcriptomic atlas of human CA using dataset...