World Journal of Radiology
Shu-Peng Wang, Zhi-Guo Chen, Xi-Jing Shan et al.
· 0 citations
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Open access
Sep 2026
Targeting LGALS1 via CAF‐Derived Extracellular Vesicles Synergizes With αPD‐1 to Reverse Immunosuppression and Sensibilize Chemo‐Immunotherapy for Colorectal Cancer
Colorectal cancer (CRC) exhibits intrinsic resistance to conventional therapeutic regimens. By integrating single‐cell and bulk transcriptomic data from CRC cohorts, we demonstrate that proliferative capacity alone constitutes an inadequate prognostic predictor. Instead, an immunosuppressive tumor microenvironment (TME...
Si-Jia Chen, Li-Shan Wang, Lin-Zhe Su et al.
· Macromolecular Bioscience · 0 citations