Oct 2026
TRIM65 deficiency exacerbates HFD-induced obesity in mice associated with elevated adipose tissue inflammation and lipid accumulation.
Obesity is linked to metabolic and cardiovascular complications, such as atherosclerosis, type 2 diabetes (T2DM), and hypertension. Despite current therapies alleviate certain clinical manifestations, effective disease-modifying targets remain scarce. TRIM65 (tripartite motif-containing 65) has been linked to carcinoge...
Wen-Han Wei, Dan Wang, Xiang-Nuo Han et al.
· International Immunopharmaco... · 0 citations