A Self-Amplifying Ultrasound-Activated Polymeric Prodrug Nanoplatform for Synergistic Sonodynamic Immunotherapy.
Ultrasound (US)-triggered sonodynamic therapy (SDT) combined with immunotherapy shows considerable promise, yet its therapeutic efficacy remains constrained by insufficient intratumoral drug activation and limited immunogenicity. Herein, we report a self-amplifying US-responsive nanoplatform (PMB@R848) for synergistic...