Regio- and Stereoselective Synthesis of Anticancer Imidazo[1,2-a]pyridine-chromones Assisted by Hydrogen Bonding.
Numerous 1,2- or 1,4-addition reactions of imidazo[1,2-a]pyridines across unsaturated C═N or C═C bonds have been extensively studied. Regioselective 1,4-conjugate addition with the aid of hydrogen bonding remains unexplored. Herein, a regioselective and stereoselective approach for the synthesis of imidazo[1,2-a]pyridi...