A Manganese-Chlorella Hydrogel for an Integrated “Remove–Remodel–Repair” Strategy in Pancreatic Cancer Therapy
An injectable, self-healing hydrogel (CMCGel) is engineered via dynamic cross-linking of manganese ions and carboxymethyl chitosan to load chlorella extract. The pH/laser dual-responsive platform with endogenous pH gating and exogenous laser switching enables a programmed “Remove–Remodel–Repair” (3R) strategy. CMCGel a...