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Author

Xin-Jian Guo

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Open access Aug 2026

Neural Engineering Tailored by Molecular Motors With Self-Reporting for Neuron Activation and Depression Treatment.

The discovery of mechanical regulation to neuronal behavior offers a novel perspective for understanding nervous system function and advancing neural engineering. A key challenge lies in achieving precise mechanical control of neurons while simultaneously monitoring their activity in real time. Here, we engineered a no...

Pengpeng Lu, Xin-Jian Guo, Tao Liu et al. · 0 citations
Sep 2026

NQO1‑activated self‑reinforcing bimetallic nanoplatform triggers ferroptosis and cuproptosis for osteosarcoma therapy.

The CFCM/VK3 nanoplatform demonstrates significant tumor suppression and excellent biosafety in an osteosarcoma mouse model, establishing a new paradigm of metal-ion interference therapy that leverages the mutual dependency between iron and copper for self-amplifying antitumor effects.

Ye Zhang, Qing-Qing Bai, Yan-Hua Zhong et al. · 0 citations

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