Open access
Sep 2026
Structure of the MurA-LpxC enzyme complex in modulating peptidoglycan and lipopolysaccharide biosynthesis.
Cryo-electron microscopy (cryo-EM) structures of the Pseudomonas aeruginosa MurA-LpxC complex in the absence and presence of the LpxC inhibitor CHIR-090 are determined, providing molecular insights into complex formation.
Joshua Yi Yeo, Xin-Fu Yan, Zhu Qiao et al.
· Journal of Structural Biolog... · 0 citations