Xin-Feng Yang

Type I collagen promotes triple-negative breast cancer progression through a UBE2V1–ACSL5 regulatory axis

Introduction Triple-negative breast cancer (TNBC) is characterized by aggressive behavior and extensive extracellular-matrix remodeling. Type I collagen (COL I), a major stromal component, promotes tumor progression, but the downstream tumor-cell mechanisms remain incompletely defined. We investigated whether COL I reg...