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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Xiaozheng Zhang

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Open access Jul 2026

Reduced FOXO1 expression is associated with tumor progression through metabolic and immune dysregulation in kidney renal clear cell carcinoma

Kidney renal clear cell carcinoma (KIRC), the most aggressive subtype of renal cancer, is characterized by metabolic reprogramming and an immunosuppressive microenvironment. While forkhead box O1 (FOXO1) is recognized as a pleiotropic regulator of cellular metabolism and immune responses, its potential tumor-suppressiv...

Wenyi Hou, Meng-wei Wang, Xiaozheng Zhang et al. · 0 citations

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