Author

Xiaoyong Tong

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Open access Jul 2026

Inactivation of SERCA2 at Cys674 induces skeletal muscle atrophy by activating the TGFβ/Smad-S100a4 axis to promote inflammation

The SERCA2-RAS-TGF-β/Smad-S100a4 signaling axis emerges as a highly promising therapeutic target for mitigating disuse-induced skeletal muscle wasting.

Fei Nan, Siyao Liu, Shunyi Lei et al. · Redox Biology · 0 citations