Xiao-Long Zhang

CMAF-DDI: A Knowledge-Enhanced Cross-Modal Fusion Method Leveraging Protein Representation for Multi-Class Drug-Drug Interactions.

Experimental results show that CMAF-DDI improves multi-class DDI prediction compared with representative graph-based and multi-source fusion baselines and ablation, hyperparameter sensitivity, controlled protein perturbation, representation, and case-level analyses to examine the contribution and behavior of protein-enhanced cross-modal fusion.