Author

Xiaolong Wang

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Open access Jul 2026

Multi-omics and functional validation reveal that Methanobrevibacter-derived L-3-aminoisobutyrate alleviates subclinical mastitis in dairy goats via the HSPA1B-p65 signaling pathway.

This study identifies BAIBA as a microbiota-derived metabolite that protects against SCM by restraining mammary inflammation via the HSPA1B-NF-κB axis, establishing a mechanistic gut-mammary link and highlighting a potential non-antibiotic intervention strategy.

Yu Lei, Yangbin Xu, Yiting Yan et al. · Microbiome · 0 citations

Open access Jul 2026

Shared CRISPR arrays underpin type I-A/I-B coexistence.

A shared-array logic in which Cas6a/Cas6b-compatible processing routes a single pre-crRNA to multiple type I effectors providing a potential mechanism for subtype co-existence, a plausible explanation for array-less (or "orphan") interference modules, and an evolutionary bet-hedging strategy that prevents Acrs from shutting down immunity wholesale are uncovered.

Kunming Liu, Chunjiang Ren, Xinyue Liu et al. · Protein & Cell · 0 citations