Author

Xiaojing Ke

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Open access Aug 2026

Association between sodium-glucose cotransporter 2 inhibitors and the risk of chronic lower respiratory disease in type 2 diabetes mellitus: findings from two target trial emulations

Research on the association between sodium‑glucose cotransporter 2 inhibitors (SGLT-2i) and chronic lower respiratory diseases (CLRDs) in patients with type 2 diabetes (T2DM) remains limited. This study aimed to investigate this association and examine the potential modifying effects such as age, sex, and diabete...

Yu-Hao Li, Yiqiao Lv, Yong-Qi Dai et al. · Respiratory Research · 0 citations

Open access Aug 2026

Molecular Mechanisms of Podophyllotoxin-Induced Subacute Kidney Injury: Oxidative Stress-Mediated Activation of the TRPM2-NOD-NF-κB Pathway.

PT induces subacute kidney injury involving oxidative stress and TRPM2-NOD-NF-κB-related inflammatory signalling and JNJ-28583113 attenuated PPT-induced ROS accumulation, apoptosis, Nod1/Nod2 expression, and NF-κB p65 phosphorylation.

Lulu Chen, Zi-Long Chen, Xin-Ze Li et al. · Environmental Toxicology and... · 0 citations