Author

Xiaohui Luo

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Open access Aug 2026

Apoptosis-related genes bridge inflammatory bowel disease and osteoporosis: A bioinformatic analysis

Background Inflammatory bowel disease (IBD) and osteoporosis (OP) often co-occur, with IBD accelerating OP onset, though the underlying mechanisms remain unclear. Methods Based on gene expression data from the GEO database, differential expression analysis was performed using the limma package to identify genes dysregu...

Yu Su, Xiao-Hui Luo, Hai-Tao Xu · PLoS ONE · 1 citation

Review Aug 2026

Advances in the study of the role of bone immunity in physiological and pathological processes related to bone metabolism.

BACKGROUND Bone metabolism is regulated by immune cells that maintain skeletal homeostasis through cytokine secretion and cell interactions. Disruption of this regulation-by inflammation, autoimmunity, or aging-drives pathological bone diseases including osteoporosis and rheumatoid arthritis. Single-cell technologies a...

Zhuoru Jin, Lisheng Liu, He-Ran Wang et al. · International Immunopharmaco... · 0 citations