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Author

Xiaohua Chen

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Review Open access Aug 2026

Immunological Mechanisms of the Gut–brain–cardiovascular Axis in Coronary Heart Disease with Comorbid Anxiety and Depression

Coronary heart disease (CHD) is frequently accompanied by anxiety and depression, conditions that markedly worsen cardiovascular outcomes. Increasing evidence indicates that immune dysregulation, driven by gut microbiota alterations, plays a central role in linking psychological disorders with cardiovascular pathology...

Yi-Wei Xu, Xiaohua Chen · 0 citations
Open access Aug 2026

Genetic evidence for a causal role of depression in late-onset Alzheimer disease: A Mendelian randomization study

Genetic evidence supporting a causal role for depression in the etiology of late-onset AD is provided, a link not observed for other major psychiatric disorders tested and highlighted the specific importance of managing depression as a potential strategy for mitigating AD risk.

Yan-Lin Chen, Xiao-Hua Chen · 0 citations

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