Sep 2026
BACKGROUND
In glioblastoma (GBM), epidermal growth factor receptor (EGFR) amplification, one of the most prevalent genetic alterations, often occurs on extrachromosomal DNAs (ecDNAs) that contain amplified oncogenes and regulatory elements, driving tumor progression. Despite the central oncogenic role of EGFR amplifica...
Xiao-Zhou Yu, Run-Xin Wu, Tian-Zhi Huang et al.
· Neuro-Oncology · 0 citations
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Open access
Sep 2026
Abstract Background Non-small cell lung cancer (NSCLC) is one of the frequently occurring cancers characterized by molecular heterogeneity and multiple immune cell infiltration patterns, which are associated with treatment sensitivity and resistance. However, the specific microenvironmental cells and their mechanisms t...
Yao-Yao Zhou, Zi-Yun Liu, Parhat Kaysar et al.
· Journal for ImmunoTherapy of... · 0 citations
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Sep 2026
Therapeutic disruption of this splicing program may represent a strategy to enhance the radiation response in recurrent IDH-mutant glioma.
Qiu He, Run-Xin Wu, Xiao-Zhou Yu et al.
· Neuro-Oncology · 0 citations
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