Spontaneous wbbL and waaG mutations selected by phage vB_EcoP_P61425 confer resistance and attenuate virulence in ExPEC
Bacteriophage therapy is a promising strategy against multidrug-resistant (MDR) extraintestinal pathogenic Escherichia coli (ExPEC), yet bacterial resistance evolution remains a major clinical challenge. In this study, we isolated and comprehensively characterized a novel lytic phage, vB_EcoP_P61425, belonging to t...