Open access
Jul 2026
Single‐Cell RNA Sequencing Reveals Disrupted Stromal–Epithelial Crosstalk Impairs Gut Barrier in Depression
Depressive disorder is commonly associated with gastrointestinal dysfunction, but the specific cellular and molecular alterations within the colonic mucosa remain poorly understood. The role of stromal–epithelial crosstalk in the colonic niche under depressive conditions is particularly unclear.
Xiao-Song Xu, Wan-Ning Zhang, Xu-Rui Hao et al.
· Brain and Behavior · 0 citations