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Author

Xiao-Yu Hu

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Open access Sep 2026

Genetic organization and mobile-element basis of β-lactam resistance in a polyclonal respiratory Haemophilus influenzae population

Haemophilus influenzae is an important respiratory colonizer and opportunistic pathogen. In the post-Hib vaccine era, non-type b and nontypeable strains have become increasingly associated with clinical disease, while β-lactam resistance complicates treatment and surveillance. To investigate the genet...

Xiao-Mei Xu, Yu-Peng Luo, Jun-Tao Tan et al. · 0 citations
Open access Sep 2026

Deciphering early molecular responses to aristolactam I associated with hepatocellular carcinoma: Computational prediction of a core gene signature and identification of transcription-translation uncoupling under acute aristolactam I exposure.

Aristolochic acid I (AAI) is a potent hepatocarcinogen mainly activated to aristolactam I (ALI). The molecular mechanisms driving ALI‑associated hepatocellular carcinoma (HCC), particularly post‑transcriptional events linking acute liver injury to malignant transformation, remain poorly defined. Here, we integrated pha...

Qing Peng, L. Hao, Sheng-Hao Li et al. · 0 citations

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