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Author

Xiao Yang

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Open access Oct 2026

Multimodal analysis identifies a fibroblast subtype enriched in EGFR-mutant NSCLC and its spatial niches

A mutation-specific stromal-tumor-immune regulatory network is revealed and the COL16A1-integrin β1 pathway is established as a rational therapeutic target to enhance the efficacy of osimertinib and pembrolizumab in EGFR -mutant NSCLC.

Xiao Yang, Xiao-Qing Wang, Min Zhang et al. · 0 citations

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