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Xiao-Yan Wang

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Open access Oct 2026

161Tb Radiopharmaceutical Therapy as a Treatment for RANKL-Positive Multiple Myeloma.

BACKGROUND Denosumab, an anti-RANKL monoclonal antibody, is clinically approved for bone protection in multiple myeloma (MM) but lacks direct cytotoxic effects on tumor cells. Herein, we repurpose this well-tolerated antibody as a targeted delivery vehicle by conjugating it with the emerging radionuclide 161Tb, which e...

Hao-Yi Yan, Jun Li, Chuan-Mian Xu et al. · 0 citations

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