Linoleic Acid-Lyso PG Axis promoting lipid droplet–mitochondria tethering by stabilizing Noncanonically Mitochondrial PPAR β/δ to Ameliorate Microglial Dysfunction in subarachnoid hemorrhage
The LA–LPG(16:0)–PPARδ axis links glycerophospholipid remodeling to organelle coupling and mitochondrial recovery in microglia after SAH, and reduces neuroinflammatory injury and partially improved anxiety- related behavior and spatial memory in mice.