Xiao-Xi Du

Crosstalk between innate immune signaling pathways and integrated TLR, NLRP3 inflammasome, cGAS–STING, and NF-κB networks in sepsis

Sepsis is a life-threatening syndrome characterized by a dysregulated host response to infection that culminates in systemic inflammation, immune dysfunction, and multiple organ failure. Despite advances in supportive care, the molecular mechanisms underlying sepsis remain incompletely understood, largely due to the co...