Open access
Aug 2026
Systematic genomic Mendelian randomization profiling of early molecular markers of optic atrophy.
Mediation analysis indicated that Upper zone of growth plate and cartilage matrix associated (UCMA) potentially mediates the effect of SEC61A2 in increasing OPA risk and SEC61A2 likely increases OPA risk through UCMA.
Jun-Zhao Yang, Yan-Ting Liu, Xinsen Liu et al.
· International Journal of Oph... · 0 citations