Xiao-Tong Chen

Untargeted metabolomics reveals L-Lysine depletion as a host-directed therapeutic target in Toxoplasma gondii infection.

Toxoplasmosis is a widespread zoonotic disease causing severe outcomes in immunocompromised individuals and during pregnancy. Current therapeutic options target actively replicating stages of the parasite and show limited efficacy against chronic infection. While research has focused on parasite-directed therapies, hos...