Single-Cell Transcriptomic Analysis Reveals Age-Associated Cellular and Transcriptional Changes in Murine Lacrimal Glands.
Purpose To characterize age-associated changes in lacrimal gland cellular composition, transcriptional states, and intercellular communication and to explore their relationship with lacrimal gland dysfunction and age-related dry eye disease (DED). Methods Single-cell RNA sequencing (scRNA-seq) was performed on extrao...