Review
Open access
Aug 2026
YBX1 as an adaptive RNA hub in cancer: linking state-dependent RNA regulation to tumor immunity, metabolic reprogramming, and therapy resistance
Evidence suggests that tumor-specific dependency is carried by the configuration of the YBX1/YBX2/YBX3 family rather than by any single member, and reframing shifts the actionable question from whether YBX1 is high to which YBX1-dependent circuit a tumor uses.
Xiao-Tian Zhang, Yi-Tong Wang, Chong-Chong Feng
· Frontiers in Immunology · 0 citations