Author

Xiao-Qian Yan

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Open access Sep 2026

Postnatal maturation of putamen microstructure accompanies topographic white matter connectivity and altered circuits in autism

The putamen is a major hub of the basal ganglia that emerges early in gestation. However, whether its mature organization is established before birth or emerges postnatally remains unknown. Using cross-sectional and longitudinal quantitative MRI (R1 and R2*, related to tissue density and iron, respectively), and diffus...

Vaidehi S. Natu, Christina Tyagi, Xiao-Qian Yan et al. · bioRxiv · 0 citations

Open access Aug 2026

Deep learning reveals a neurocomputational mechanism predicting depression risk in adolescents

Early detection and prevention of psychiatric disorders, particularly depression, remain as major global health challenges, yet reliable tools for identifying individuals before symptom onset are lacking. Here, we combine functional neuroimaging with computational modeling to identify a mechanistic biomarker of depress...

Han Lu, Xiaoqian Yan, Benjamin Becker et al. · Science Advances · 0 citations