Author

Xiao-Mei He

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Review Open access Oct 2026

NK Cell Technology for Tumour Treatment: Advances, Advantages, Challenges, and Clinical Prospects

The natural cytotoxic properties of natural killer (NK) cells together with their suitability for genetic modification have attracted increasing interest in tumour immunotherapy. This review evaluates how NK cell-based therapies have developed, with particular attention to chimeric antigen receptor (CAR)-NK technology,...

Xiao-Mei He · Theoretical and Natural Scie... · 0 citations

Open access Sep 2026

Single-cell and bulk transcriptomic integration identifies a high-CNV, dark-zone-enriched malignant cell state associated with adverse prognosis in GCB-DLBCL.

BACKGROUND Germinal centre B-cell-like diffuse large B-cell lymphoma (GCB-DLBCL) generally has a better prognosis than activated B-cell-like DLBCL, yet a clinically significant subset of patients still develops aggressive disease, suggesting marked malignant cellular heterogeneity within this subtype. This study aimed...

Jia-Ning Wang, Xiu-Ying Xiang, Xiao-Mei He et al. · Hematology · 0 citations