Xiao-Lei Zhu

Structure-Based Discovery of Trifluoromethyl Oxadiazole Oxime Ethers as Potent Histone Deacetylase Inhibitors.

TFMO-oxime ethers are identified as promising scaffolds for HDAC-targeted fungicide discovery in Pseudomonas aeruginosa HDAC, and most derivatives showed potent inhibitory activity against Pa-HDAC.