Author

Xiao-Lei Xu

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Open access Sep 2026

Hepatic arterial infusion chemotherapy plus lenvatinib with or without PD-1 inhibition for unresectable hepatocellular carcinoma: a retrospective cohort study.

The benefit of adding programmed cell death protein 1 (PD-1) blockade to hepatic arterial infusion chemotherapy (HAIC) plus lenvatinib for unresectable hepatocellular carcinoma remains uncertain. This single-center retrospective cohort study included 373 patients. After propensity score matching, 107 patients treated w...

Hai-Dong Yu, Cun-Kai Ma, C. Yangdan et al. · Journal of chemotherapy · 0 citations

Open access Sep 2026

PD-L1+ neutrophils at the invasive margin drive contact-dependent CD8+ T cell exhaustion in hepatic alveolar echinococcosis

Introduction Hepatic alveolar echinococcosis (HAE), a lethal chronic helminth infection caused by Echinococcus multilocularis, is characterized by pronounced local immune evasion and progressive CD8+ T cell exhaustion at the parasite?host invasive margin. However, the spatial cellular network and core regulatory subset...

Da-Lin Shi, Chengwei Tie, Ming-Quan Pang et al. · Frontiers in Immunology · 0 citations