Open access
Aug 2026
SLC3A1 Mitigates Ferroptosis and Promotes Enzalutamide Resistance in Prostate Cancer
ABSTRACT Prostate cancer (PCa) remains a leading cause of cancer‐related mortality in aging male, with resistance to enzalutamide (Enza) representing a major therapeutic challenge. This study identifies SLC3A1 as a key driver of Enza resistance. Through integrative bioinformatics analysis of GEO datasets, we found SLC3...
Peng Liu, Hao-Cheng Zhang, Yuhang Qian et al.
· Journal of biochemical and m... · 0 citations