Krüppel-like Factors in Autophagy: A Spatiotemporal Rheostat Framework Linking Cellular Fate and Disease
Macroautophagy/autophagy links environmental cues to cellular adaptation, differentiation, and pathology. Krüppel-like factors (KLFs) influence autophagy across diverse contexts, yet their effects differ in direction and biological outcome, challenging a simple activation-versus-inhibition model. This perspective pr...