Author

Xiao-Hui Wang

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Open access Sep 2026

Striatal temporal interference stimulation alleviates motor deficits and confers neuroprotection in an MPTP-induced mouse model of Parkinson’s disease with associated improvements in mitochondrial homeostasis

Temporal interference (TI) stimulation is an emerging noninvasive neuromodulation approach capable of selectively targeting deep brain structures, but its therapeutic effects and underlying mechanisms in Parkinson’s disease (PD) remain unclear. Here, we evaluated striatal TI stimulation in an MPTP-induced mouse model o...

Jin Peng, Zi-Yu Wang, Yu Liu et al. · Neurotherapeutics · 0 citations

Review Aug 2026

Deep-brain Neuromodulation in Parkinson's Disease: Convergent Mechanisms and Translational Stratification of Deep Brain Stimulation and Low-intensity Focused Ultrasound.

Overall, deep-brain neuromodulation in PD should be viewed as a multi-dimensional therapeutic framework rather than a group of isolated technologies, and DBS remains the clinical benchmark, with durable motor benefits and an expanding mechanistic framework that now extends beyond circuit correction to neurotrophic, pro...

Jin Peng, Yu Liu, Xiao-Hui Wang · Ultrasound in Medicine and B... · 0 citations