Open access
Aug 2026
Establishing the Median Effective Dose of Tegileridine for Immediate Postoperative Analgesia Following Laparoscopic Colorectal Cancer Surgery: A Sequential Dose-Finding Study
Background: To determine the median effective dose (ED 50 ) of tegileridine for immediate postoperative analgesia following laparoscopic colorectal cancer surgery (LCRS), and to evaluate its safety profile. Methods: A modified Dixon’s up-and-down sequential method was employed, starting with an initial tegileridine dos...
Minna Guo, Tong Wang, Shuchi Lin et al.
· Drug Design, Development and... · 0 citations