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Xiao-Hang Yang

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Case report Open access Sep 2026

A homozygous SPDYA variant associated with meiotic arrest and failed microdissection testicular sperm extraction in non-obstructive azoospermia

Background Non-obstructive azoospermia (NOA) with meiotic maturation arrest is a severe form of male infertility for which genetic diagnosis may inform counseling and sperm-retrieval expectations. Methods Whole-exome sequencing was performed in a consanguineous family with NOA, followed by SPDYA variant screening in 31...

Hui-Mei Zheng, Yun-Bo Wang, Jia Wang et al. · 0 citations

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