T-2 toxin induces glycometabolic reprogramming in chondrocytes via a MALAT1/p38‑mediated ceRNA regulatory axis.
T-2 toxin is a widely distributed dietary mycotoxin and a key environmental driver of Kashin-Beck disease (KBD), yet the molecular events linking exposure to cartilage injury remain incompletely defined. We examined the chondrotoxic mechanism of T-2 toxin through a MALAT1/miR-15b-5p/MAP2K3 competing endogenous RNA (ceR...