Xiao-Han Li

10-gingerol potentiates paclitaxel efficacy in triple-negative breast cancer by remodeling gut microbiota and suppressing PI3K/AKT/mTOR signaling pathway.

Triple-negative breast cancer (TNBC) remains a clinical challenge due to its aggressive nature and chemoresistance, particularly to first-line agents such as paclitaxel (PTX). 10-Gingerol (10-G), the main pungent constituent of ginger, has been shown to possess anti-tumor and chemosensitizing properties. However, the m...