Author

Xiao-Feng Yang

3 papers indexed here

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Open access Sep 2026

Injury polarized CD4+ T cells orchestrate redox and unfolded protein responses to promote cardiac repair after myocardial infarction

Myocardial infarction (MI) initiates a wound-healing response where immune cells shape inflammation, tissue repair, and long-term remodeling. Although CD4+ T cells are increasingly recognized as contributors to post-MI healing, the transcriptional reprogramming defining their early pro-reparative functions remains inco...

Thomas W. C. Knight, Fatma Saaoud, Ngefor Asangwe et al. · Redox Biology · 0 citations

Open access Sep 2026

Integrative Omics Analysis Reveals a CD206+ Macrophage/Dendritic Cell–CD155–TIGIT+ Regulatory T Cell Axis as a Protective Immune Checkpoint Pathway in Atherosclerosis Progression

RNA sequencing (RNA-seq) analysis revealed transcriptional features indicative of sustained immunosuppression within regulatory T cells (Tregs) isolated from atherosclerotic tissues, highlighting the critical contribution of immune checkpoint (ICP) receptor–ligand interactions to atherosclerosis progression. To compreh...

Ying Shao, Fatma Saaoud, Mohammed Ben Issa et al. · Barrier immunity · 0 citations

Review Open access Sep 2026

The regulatory and therapeutic potential of transposable elements in cancer and inflammatory diseases.

The classification and regulatory functions of TEs are summarized, their roles in immune regulation, inflammation and cancer, and emerging therapeutic strategies targeting TE-associated pathways in cancer and inflammatory diseases are examined.

Ke-Man Xu, Juan-Juan Liu, Fatma Saaoud et al. · Pharmacology and Therapeutic... · 0 citations