Resampling-Iteration-Evolution (RIE): A Rational Design System for Engineering High-Affinity Peptides against Small Molecules.
A computational design pipeline, termed resampling-iteration-evolution (RIE), for the rapid discovery of high-affinity molecular recognition peptides (MRPs) from large structural and sequence databases is reported, establishing RIE as a rapid and effective in silico platform for the development of peptide binders for s...