Author

Xiao-Fan Yin

2 papers indexed here

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Review Open access Sep 2026

Immunotherapy of membranous nephropathy: strategic evolution from CD20 monoclonal antibodies to future vaccines

Membranous nephropathy (MN) arises from autoantibody-mediated attack on podocyte antigens, with immune deposits forming subepithelially at the glomerular basement membrane to trigger complement activation and subsequent podocyte damage, eventually manifesting as proteinuria. Traditional therapy hinges on nonspecific im...

Ke-Na Yu, Xi-Fang Xu, Jun-Wei Gao et al. · Frontiers in Immunology · 0 citations

Open access Sep 2026

The active ingredient madecassoside in Huyan no. 1 formula ameliorates D-gal-induced renal aging through the AMPK/MAPK/AP-1 signaling pathway.

BACKGROUND Renal aging accelerates overall organismal aging. The traditional Chinese medicine formula Huyan I (HY-1) has been shown to slow the decline in kidney function, but its pharmacological mechanism is unclear. This study focuses on its active component, madecassoside (MA), aiming to elucidate how it delays rena...

Li-Yan Huang, Si-Yao Yu, Yi-Ning He et al. · International Immunopharmaco... · 0 citations