Progressive probing and iterative integration enable strain-state-specific fine-tuning of the MEP pathway for patchoulol biosynthesis in Bacillus subtilis
Efficient optimization of metabolic pathways in microbial cell factories remains challenging because the relative contributions of individual pathway enzymes can change with the metabolic state of engineered strains. Conventional metabolic engineering approaches generally rely on predefined targets or simultaneou...
Ya-Feng Song, Zhen-Long Ding, Xing-Ying Yang et al.
· Microbial Cell Factories · 0 citations