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Xiangyu Li

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Open access Aug 2026

PAM-DB: Revealing Protein Activation Mechanisms for Next-Generation Rational Drug Discovery

A structural database that systematically maps the complete activation trajectories of pharmaceutically relevant targets, encompassing TS, IS, and all connecting conformational ensembles is presented, offering multiple strategic advantages for drug discovery.

Xiaohong Zhu, Xiangyu Li, Yaning Hou et al. · 0 citations

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